Basic Information
ID: ALA4313633
Type: ADME
Description: Drug metabolism in Sprague-Dawley rat liver microsomes assessed as CYP450-mediated 2-[[2-(aminomethyl)-3-[3,5-bis(trifluoromethyl)phenyl]-2-[[3,5-bis(trifluoromethyl)phenyl]methyl]propanoyl]amino]acetic acid formation incubated up to 3 hrs in presence of NADPH regenerating system by RP-HPLC-MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4313633
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 583.42 | 5.57 | 5.57 |