Basic Information
ID: ALA4313636
Type: ADME
Description: Drug metabolism in Sprague-Dawley rat liver microsomes assessed as CYP450-mediated N-(2-aminoethyl)-2-(aminomethyl)-2-[(4-fluoro-5,6-dihydroxy-5,6-dihydronaphthalen-1-yl)methyl]-3-(4-fluoro-1-naphthyl)propanamide formation incubated up to 3 hrs in presence of NADPH regenerating system by RP-HPLC-MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4313636
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.53 | 4.08 | 4.08 |