Basic Information
ID: ALA4313844
Type: ADME
Description: Inhibition of human microsomal CYP2D6 expressed in baculovirus infected insect cells at 10 uM using luciferin-ME as substrate preincubated with enzyme/substrate mixture for 30 mins followed by further incubation with NADPH for 30 mins by CYP450 luciferase Glo assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4313844
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.58 | 5.68 | 5.68 |
| 274.30 | 3.24 | 3.24 |
| 308.36 | 4.69 | 4.69 |
| 288.32 | 3.54 | 3.54 |
| 366.39 | 4.61 | 4.61 |
| 288.32 | 3.54 | 3.54 |
| 274.30 | 3.24 | 3.24 |
| 288.32 | 3.54 | 3.54 |
| 373.23 | 5.14 | 5.14 |
| 328.78 | 5.03 | 5.03 |
| 293.28 | 3.35 | 3.35 |
| 312.28 | 2.90 | 2.90 |
| 244.20 | 2.46 | 2.46 |
| 272.32 | 3.84 | 3.84 |
| 395.44 | 4.74 | 4.74 |
| 294.33 | 4.38 | 4.38 |
| 244.20 | 2.46 | 2.46 |
| 324.36 | 4.39 | 4.39 |
| 258.23 | 2.77 | 2.77 |
| 312.32 | 4.52 | 4.52 |
| 274.30 | 3.24 | 3.24 |
| 307.31 | 3.66 | 3.66 |
| 312.32 | 4.52 | 4.52 |
| 319.32 | 3.72 | 3.72 |
| 338.38 | 4.78 | 4.78 |
| 258.23 | 2.77 | 2.77 |
| 352.41 | 5.08 | 5.08 |
| 272.32 | 3.84 | 3.84 |
| 308.36 | 4.69 | 4.69 |
| 321.33 | 3.67 | 3.67 |
| 362.34 | 3.95 | 3.95 |
| 408.48 | 5.78 | 5.78 |
| 366.44 | 5.47 | 5.47 |
| 388.38 | 4.57 | 4.57 |
| 328.78 | 5.03 | 5.03 |
| 288.32 | 3.54 | 3.54 |
| 404.42 | 4.86 | 4.86 |
| 324.36 | 4.39 | 4.39 |
| 408.48 | 5.63 | 5.63 |