Basic Information
ID: ALA4314077
Type: Binding
Description: Inhibition of recombinant N-terminal GST-tagged human FAK (327 to 1052 residues) expressed in baculovirus expression system using TK as substrate incubated for 50 mins in presence of ATP and measured after 1 hr by HTRF assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Focal adhesion kinase 1(ALA2695)
Document: ALA4311976
Inhibition of recombinant N-terminal GST-tagged human FAK (327 to 1052 residues) expressed in baculovirus expression system using TK as substrate incubated for 50 mins in presence of ATP and measured after 1 hr by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4314077
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.95 | 3.82 | 3.82 |
| 537.65 | 3.55 | 3.55 |
| 479.57 | 3.07 | 3.07 |
| 415.46 | 3.16 | 3.16 |
| 517.57 | 4.52 | 4.52 |
| 381.38 | 3.43 | 3.43 |
| 447.50 | 2.99 | 2.99 |
| 389.42 | 2.50 | 2.50 |
| 533.57 | 4.18 | 4.18 |
| 452.46 | 2.98 | 2.98 |
| 442.49 | 4.27 | 4.27 |
| 503.55 | 4.17 | 4.17 |
| 521.54 | 4.31 | 4.31 |
| 492.52 | 4.54 | 4.54 |
| 517.57 | 4.48 | 4.48 |
| 550.63 | 4.92 | 4.92 |
| 571.54 | 5.19 | 5.19 |
| 494.50 | 2.75 | 2.75 |
| 434.44 | 4.05 | 4.05 |
| 450.49 | 3.81 | 3.81 |
| 451.47 | 4.24 | 4.24 |
| 504.53 | 4.60 | 4.60 |
| 521.54 | 4.31 | 4.31 |
| 484.52 | 3.99 | 3.99 |
| 550.63 | 4.92 | 4.92 |
| 461.51 | 4.10 | 4.10 |
| 442.49 | 4.27 | 4.27 |
| 490.50 | 4.17 | 4.17 |
| 425.43 | 3.54 | 3.54 |
| 547.60 | 4.57 | 4.57 |
| 475.54 | 4.44 | 4.44 |
| 434.44 | 4.65 | 4.65 |
| 551.56 | 4.32 | 4.32 |
| 473.54 | 3.65 | 3.65 |
| 503.55 | 4.17 | 4.17 |
| 431.39 | 4.15 | 4.15 |
| 503.55 | 4.17 | 4.17 |
| 489.52 | 3.74 | 3.74 |
| 561.63 | 4.96 | 4.96 |
| 499.45 | 5.68 | 5.68 |