Basic Information
ID: ALA4314255
Type: Binding
Description: Disaggregation of Cu2+ induced preformed fibrils of amyloid beta (1 to 42) at 25 uM preincubated with Cu2+ for 24 hrs followed by compound addition and measured after 24 hrs by thioflavin-T based fluorescence assay relative to control
Format: BAO_0000019
Target: Unchecked(ALA612545)
Document: ALA4311983
Disaggregation of Cu2+ induced preformed fibrils of amyloid beta (1 to 42) at 25 uM preincubated with Cu2+ for 24 hrs followed by compound addition and measured after 24 hrs by thioflavin-T based fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4314255
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.50 | 4.36 | 4.36 |
| 368.39 | 3.37 | 3.37 |
| 506.69 | 5.80 | 5.80 |
| 454.61 | 4.73 | 4.73 |
| 510.72 | 6.29 | 6.29 |
| 534.74 | 6.58 | 6.58 |
| 506.69 | 5.80 | 5.80 |
| 478.63 | 5.02 | 5.02 |
| 714.99 | 9.52 | 9.52 |
| 590.85 | 8.14 | 8.14 |
| 658.88 | 7.96 | 7.96 |
| 562.80 | 7.36 | 7.36 |
| 686.94 | 8.74 | 8.74 |
| 482.67 | 5.51 | 5.51 |
| 566.83 | 7.85 | 7.85 |
| 771.10 | 11.08 | 11.08 |
| 450.58 | 4.24 | 4.24 |
| 478.63 | 5.02 | 5.02 |