Basic Information
ID: ALA4314453
Type: Binding
Description: Potency index, ratio of VCH-759 IC50 to compound IC50 for HCV genotype 1a recombinant NS5B polymerase coincubated with HCV international ribosome entry site template sequence containing nucleotide residues 21-371 of HCV 5'-untranslated Escherichia coli DNA polymerase I region
Format: BAO_0000357
Organism: Hepatitis C virus subtype 1a
Target: Hepatitis C virus NS5B RNA-dependent RNA polymerase(ALA5375)
Document: ALA4311989
Potency index, ratio of VCH-759 IC50 to compound IC50 for HCV genotype 1a recombinant NS5B polymerase coincubated with HCV international ribosome entry site template sequence containing nucleotide residues 21-371 of HCV 5'-untranslated Escherichia coli DNA polymerase I region: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4314453
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.83 | 4.02 | 4.02 |
| 372.83 | 4.02 | 4.02 |
| 390.30 | 3.10 | 3.10 |
| 369.42 | 1.94 | 1.94 |
| 355.85 | 2.45 | 2.45 |
| 390.82 | 4.15 | 4.15 |