Basic Information
ID: ALA4315097
Type: Binding
Description: Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4315097
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 562.72 | 5.03 | 5.03 |
| 362.48 | 4.17 | 4.17 |
| 560.68 | 5.86 | 5.86 |
| 430.98 | 6.36 | 6.36 |
| 416.96 | 5.97 | 5.97 |
| 410.49 | 4.32 | 4.32 |
| 432.52 | 5.99 | 5.99 |
| 407.47 | 4.08 | 4.08 |
| 522.26 | 6.22 | 6.22 |
| 396.52 | 3.18 | 3.18 |
| 438.55 | 5.10 | 5.10 |
| 404.51 | 3.94 | 3.94 |
| 461.35 | 5.59 | 5.59 |
| 475.38 | 5.98 | 5.98 |
| 382.46 | 4.83 | 4.83 |
| 429.34 | 5.07 | 5.07 |
| 400.45 | 4.97 | 4.97 |
| 364.52 | 4.50 | 4.50 |
| 396.92 | 4.83 | 4.83 |
| 439.97 | 4.64 | 4.64 |
| 388.56 | 5.68 | 5.68 |
| 378.50 | 5.04 | 5.04 |
| 450.58 | 4.97 | 4.97 |
| 400.98 | 5.66 | 5.66 |
| 446.55 | 6.38 | 6.38 |
| 536.29 | 6.61 | 6.61 |
| 374.53 | 5.29 | 5.29 |
| 398.96 | 5.15 | 5.15 |
| 392.57 | 5.28 | 5.28 |
| 424.98 | 5.61 | 5.61 |
| 428.56 | 6.24 | 6.24 |
| 471.37 | 4.84 | 4.84 |
| 441.04 | 6.32 | 6.32 |
| 406.55 | 5.86 | 5.86 |
| 404.46 | 5.21 | 5.21 |
| 426.92 | 4.73 | 4.73 |
| 388.54 | 5.38 | 5.38 |
| 338.48 | 4.23 | 4.23 |
| 394.95 | 5.55 | 5.55 |
| 429.34 | 5.07 | 5.07 |
| 454.95 | 5.80 | 5.80 |
| 372.93 | 4.88 | 4.88 |
| 416.59 | 6.16 | 6.16 |
| 392.48 | 4.07 | 4.07 |
| 378.50 | 5.08 | 5.08 |
| 469.43 | 5.72 | 5.72 |
| 422.53 | 4.19 | 4.19 |
| 395.44 | 4.21 | 4.21 |
| 374.51 | 4.99 | 4.99 |
| 350.44 | 4.30 | 4.30 |
| 473.04 | 5.00 | 5.00 |
| 459.02 | 4.61 | 4.61 |
| 438.96 | 4.60 | 4.60 |
| 386.95 | 5.27 | 5.27 |
| 396.49 | 5.22 | 5.22 |
| 458.98 | 6.65 | 6.65 |
| 408.98 | 5.94 | 5.94 |
| 386.42 | 4.58 | 4.58 |
| 412.99 | 5.54 | 5.54 |
| 447.33 | 5.20 | 5.20 |
| 417.38 | 4.99 | 4.99 |
| 336.41 | 3.91 | 3.91 |
| 437.03 | 6.72 | 6.72 |
| 494.21 | 5.44 | 5.44 |
| 360.51 | 4.90 | 4.90 |
| 396.49 | 5.22 | 5.22 |
| 418.49 | 5.60 | 5.60 |
| 416.90 | 5.49 | 5.49 |
| 435.53 | 4.86 | 4.86 |
| 414.48 | 5.36 | 5.36 |
| 430.93 | 5.88 | 5.88 |
| 368.43 | 4.44 | 4.44 |
| 423.00 | 6.33 | 6.33 |
| 324.45 | 3.84 | 3.84 |
| 424.98 | 5.61 | 5.61 |
| 457.39 | 5.85 | 5.85 |
| 444.99 | 4.22 | 4.22 |
| 412.94 | 5.74 | 5.74 |
| 412.54 | 5.33 | 5.33 |
| 358.90 | 4.49 | 4.49 |
| 354.40 | 4.05 | 4.05 |
| 441.37 | 4.93 | 4.93 |
| 452.53 | 4.09 | 4.09 |
| 426.92 | 4.73 | 4.73 |
| 454.95 | 5.80 | 5.80 |
| 443.88 | 5.08 | 5.08 |
| 384.89 | 4.96 | 4.96 |
| 402.59 | 6.07 | 6.07 |
| 422.53 | 4.19 | 4.19 |
| 415.31 | 4.68 | 4.68 |
| 440.59 | 6.11 | 6.11 |
| 410.47 | 4.21 | 4.21 |
| 438.96 | 4.60 | 4.60 |
| 400.50 | 5.46 | 5.46 |
| 396.92 | 4.83 | 4.83 |
| 380.47 | 4.31 | 4.31 |
| 422.50 | 4.08 | 4.08 |
| 483.41 | 4.71 | 4.71 |
| 350.44 | 4.30 | 4.30 |
| 384.89 | 4.96 | 4.96 |
| 392.52 | 5.43 | 5.43 |
| 388.85 | 4.71 | 4.71 |
| 367.47 | 4.03 | 4.03 |
| 423.49 | 4.99 | 4.99 |
| 408.52 | 5.09 | 5.09 |
| 378.55 | 4.89 | 4.89 |
| 452.00 | 4.51 | 4.51 |
| 412.94 | 5.74 | 5.74 |
| 464.57 | 3.96 | 3.96 |
| 433.30 | 4.81 | 4.81 |
| 378.50 | 5.08 | 5.08 |
| 430.96 | 3.83 | 3.83 |
| 450.58 | 4.97 | 4.97 |
| 508.23 | 5.83 | 5.83 |
| 445.01 | 6.75 | 6.75 |
| 417.56 | 3.86 | 3.86 |
| 406.55 | 5.82 | 5.82 |
| 368.43 | 4.44 | 4.44 |
| 402.88 | 5.10 | 5.10 |
| 372.39 | 4.19 | 4.19 |
| 366.53 | 5.01 | 5.01 |
| 364.47 | 4.69 | 4.69 |
| 427.02 | 5.93 | 5.93 |
| 410.54 | 3.57 | 3.57 |
| 442.53 | 6.14 | 6.14 |