Basic Information
ID: ALA4315249
Type: Binding
Description: Inhibition of human recombinant LSD1 using fluorogenic ADHP as substrate preincubated for 30 mins followed by substrate addition measured after 10 mins by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Lysine-specific histone demethylase 1(ALA6136)
Document: ALA4311998
Inhibition of human recombinant LSD1 using fluorogenic ADHP as substrate preincubated for 30 mins followed by substrate addition measured after 10 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4315249
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.37 | 3.37 |
| 269.30 | 3.05 | 3.05 |
| 432.95 | 3.73 | 3.73 |
| 388.90 | 3.42 | 3.42 |
| 462.97 | 3.74 | 3.74 |
| 356.38 | 2.49 | 2.49 |
| 341.36 | 3.07 | 3.07 |
| 418.92 | 3.43 | 3.43 |
| 341.37 | 1.59 | 1.59 |
| 342.35 | 2.10 | 2.10 |
| 328.32 | 2.17 | 2.17 |
| 326.36 | 2.36 | 2.36 |
| 511.02 | 4.76 | 4.76 |
| 285.30 | 2.76 | 2.76 |
| 388.90 | 3.42 | 3.42 |
| 326.35 | 2.08 | 2.08 |
| 388.90 | 3.42 | 3.42 |
| 397.91 | 3.59 | 3.59 |
| 284.31 | 2.63 | 2.63 |
| 383.40 | 2.99 | 2.99 |
| 285.30 | 2.76 | 2.76 |
| 313.35 | 3.20 | 3.20 |
| 479.02 | 5.40 | 5.40 |
| 284.31 | 2.63 | 2.63 |
| 287.29 | 3.19 | 3.19 |
| 312.33 | 2.15 | 2.15 |
| 390.89 | 3.86 | 3.86 |
| 451.79 | 4.48 | 4.48 |
| 511.02 | 4.76 | 4.76 |
| 440.89 | 4.74 | 4.74 |
| 355.39 | 1.98 | 1.98 |