Basic Information
ID: ALA4315553
Type: Binding
Description: Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hrs by beta-galactosidase based chemiluminescent assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U2OS
Target: Keap1/Nrf2(ALA3038498)
Document: ALA4312006
Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hrs by beta-galactosidase based chemiluminescent assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4315553
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 177.29 | 1.25 | 1.25 |
| 310.35 | 2.44 | 2.44 |
| 144.13 | -0.11 | -0.11 |
| 406.35 | 5.10 | 5.10 |
| 435.35 | 3.39 | 3.39 |
| 419.40 | 3.84 | 3.84 |
| 310.35 | 2.44 | 2.44 |
| 430.93 | 2.74 | 2.74 |
| 310.35 | 2.44 | 2.44 |
| 401.93 | 4.46 | 4.46 |
| 468.90 | 3.75 | 3.75 |
| 467.44 | 3.61 | 3.61 |
| 352.39 | 2.22 | 2.22 |
| 418.90 | 2.87 | 2.87 |
| 417.93 | 3.69 | 3.69 |
| 388.90 | 3.08 | 3.08 |
| 339.39 | 3.06 | 3.06 |
| 417.93 | 3.69 | 3.69 |
| 388.90 | 3.08 | 3.08 |
| 385.89 | 4.34 | 4.34 |
| 439.91 | 5.47 | 5.47 |
| 381.43 | 2.83 | 2.83 |
| 417.93 | 3.69 | 3.69 |
| 455.90 | 4.70 | 4.70 |
| 377.36 | 4.07 | 4.07 |
| 417.93 | 3.69 | 3.69 |
| 400.91 | 2.74 | 2.74 |
| 422.35 | 4.34 | 4.34 |
| 417.93 | 3.69 | 3.69 |
| 455.90 | 4.70 | 4.70 |
| 455.90 | 4.70 | 4.70 |
| 455.90 | 4.70 | 4.70 |