Basic Information
ID: ALA4316096
Type: Binding
Description: Inhibition of human microsomal MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate preincubated with substrate for 10 mins followed by enzyme addition by spectrophotometric analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Target: Monoamine oxidase B(ALA2039)
Document: ALA4312023
Inhibition of human microsomal MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate preincubated with substrate for 10 mins followed by enzyme addition by spectrophotometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4316096
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.18 | 3.33 | 3.33 |
| 285.34 | 3.00 | 3.00 |
| 171.24 | 1.90 | 1.90 |
| 187.29 | 2.18 | 2.18 |
| 302.35 | 2.37 | 2.37 |
| 310.35 | 2.89 | 2.89 |
| 308.33 | 3.73 | 3.73 |
| 319.32 | 3.48 | 3.48 |
| 322.36 | 3.77 | 3.77 |
| 347.37 | 3.66 | 3.66 |
| 294.31 | 3.59 | 3.59 |
| 332.36 | 3.19 | 3.19 |
| 333.34 | 3.62 | 3.62 |