Basic Information
ID: ALA4316098
Type: Binding
Description: Inhibition of human microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as reduction in 4-hydroxyquinoline formation at 10 uM using kynuramine as substrate preincubated with substrate for 10 mins followed by enzyme inhibition by spectrophotometric analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Target: Monoamine oxidase A(ALA1951)
Document: ALA4312023
Inhibition of human microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as reduction in 4-hydroxyquinoline formation at 10 uM using kynuramine as substrate preincubated with substrate for 10 mins followed by enzyme inhibition by spectrophotometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4316098
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.34 | 3.00 | 3.00 |
| 218.21 | 2.07 | 2.07 |
| 307.35 | 3.30 | 3.30 |
| 302.35 | 2.37 | 2.37 |
| 293.32 | 3.62 | 3.62 |
| 321.38 | 3.34 | 3.34 |
| 310.35 | 2.89 | 2.89 |
| 319.32 | 3.48 | 3.48 |
| 322.36 | 3.77 | 3.77 |
| 347.37 | 3.66 | 3.66 |
| 318.33 | 3.52 | 3.52 |
| 346.39 | 3.24 | 3.24 |
| 332.36 | 3.19 | 3.19 |
| 243.22 | 1.96 | 1.96 |
| 333.34 | 3.62 | 3.62 |