Basic Information
ID: ALA4316440
Type: Binding
Description: Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mins followed by substrate addition and measured for 10 mins by FRET assay
Format: BAO_0000019
Organism: Human immunodeficiency virus 1
Target: Protease(ALA2366517)
Document: ALA4312035
Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mins followed by substrate addition and measured for 10 mins by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4316440
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.67 | 2.38 | 2.38 |
| 560.65 | 0.98 | 0.98 |
| 561.64 | 0.69 | 0.69 |
| 542.66 | 1.69 | 1.69 |
| 571.70 | 1.58 | 1.58 |
| 558.66 | 0.98 | 0.98 |
| 542.66 | 0.84 | 0.84 |
| 586.67 | 1.48 | 1.48 |
| 527.65 | 1.26 | 1.26 |
| 576.65 | 1.12 | 1.12 |
| 557.67 | 0.86 | 0.86 |
| 590.63 | 1.31 | 1.31 |
| 591.62 | 1.02 | 1.02 |
| 572.68 | 1.29 | 1.29 |
| 588.68 | 0.47 | 0.47 |
| 575.66 | 1.41 | 1.41 |
| 556.69 | 1.15 | 1.15 |
| 587.66 | 1.19 | 1.19 |
| 573.63 | 0.88 | 0.88 |
| 573.67 | 0.05 | 0.05 |
| 557.63 | 1.59 | 1.59 |
| 543.65 | 0.55 | 0.55 |
| 603.65 | 0.37 | 0.37 |
| 557.67 | 1.27 | 1.27 |
| 572.64 | 1.17 | 1.17 |