Basic Information
ID: ALA4316489
Type: Binding
Description: Binding affinity to recombinant human carbonic anhydrase 5b expressed in Escherichia coli expression system assessed as kinetic dissociation constant fluorescent thermal shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Carbonic anhydrase VB(ALA3969)
Document: ALA4312038
Binding affinity to recombinant human carbonic anhydrase 5b expressed in Escherichia coli expression system assessed as kinetic dissociation constant fluorescent thermal shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4316489
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 222.25 | -0.86 | -0.86 |
| 270.09 | 1.34 | 1.34 |
| 325.22 | 2.17 | 2.17 |
| 369.23 | 1.32 | 1.32 |
| 359.00 | 1.56 | 1.56 |
| 359.23 | 2.57 | 2.57 |
| 369.23 | 1.32 | 1.32 |
| 414.12 | 2.39 | 2.39 |
| 327.19 | 1.02 | 1.02 |
| 355.20 | 1.24 | 1.24 |
| 402.06 | 0.58 | 0.58 |
| 313.16 | 0.36 | 0.36 |
| 327.19 | 0.75 | 0.75 |
| 351.26 | 2.70 | 2.70 |
| 339.20 | 1.11 | 1.11 |
| 269.11 | 0.74 | 0.74 |
| 457.42 | 3.92 | 3.92 |
| 443.39 | 3.78 | 3.78 |
| 402.88 | 1.10 | 1.10 |
| 432.91 | 0.68 | 0.68 |
| 439.00 | 4.34 | 4.34 |
| 418.88 | 0.54 | 0.54 |
| 412.96 | 3.81 | 3.81 |
| 442.95 | 2.87 | 2.87 |
| 449.44 | 4.05 | 4.05 |
| 436.98 | 2.62 | 2.62 |
| 406.96 | 2.79 | 2.79 |
| 392.93 | 2.13 | 2.13 |
| 404.99 | 3.94 | 3.94 |
| 439.00 | 4.34 | 4.34 |
| 481.43 | 2.73 | 2.73 |
| 356.86 | 2.38 | 2.38 |
| 370.88 | 2.42 | 2.42 |
| 424.93 | 0.82 | 0.82 |
| 432.91 | 0.93 | 0.93 |
| 392.93 | 2.13 | 2.13 |
| 442.95 | 2.82 | 2.82 |
| 426.99 | 3.85 | 3.85 |
| 456.97 | 2.88 | 2.88 |
| 445.36 | 2.11 | 2.11 |
| 471.44 | 3.96 | 3.96 |
| 463.02 | 3.16 | 3.16 |
| 400.91 | 2.51 | 2.51 |
| 474.94 | 1.56 | 1.56 |
| 488.97 | 1.64 | 1.64 |
| 406.96 | 2.52 | 2.52 |
| 400.91 | 2.25 | 2.25 |
| 434.97 | 3.01 | 3.01 |
| 477.36 | 0.79 | 0.79 |
| 480.99 | 1.78 | 1.78 |
| 459.39 | 2.15 | 2.15 |
| 464.95 | 2.75 | 2.75 |
| 411.34 | 1.71 | 1.71 |
| 471.00 | 3.02 | 3.02 |
| 455.00 | 3.36 | 3.36 |
| 437.38 | 2.24 | 2.24 |
| 349.86 | 3.11 | 3.11 |
| 424.93 | 0.82 | 0.82 |
| 431.02 | 4.47 | 4.47 |
| 386.88 | 1.86 | 1.86 |
| 438.96 | 1.21 | 1.21 |
| 432.95 | 4.07 | 4.07 |
| 400.91 | 2.00 | 2.00 |
| 442.95 | 2.82 | 2.82 |
| 447.33 | 0.99 | 0.99 |
| 342.83 | 2.24 | 2.24 |
| 456.97 | 2.96 | 2.96 |
| 424.98 | 4.20 | 4.20 |
| 471.00 | 3.02 | 3.02 |
| 398.94 | 3.67 | 3.67 |
| 475.39 | 2.46 | 2.46 |
| 371.87 | 3.02 | 3.02 |
| 412.92 | 2.61 | 2.61 |
| 438.96 | 1.47 | 1.47 |
| 469.38 | 0.93 | 0.93 |
| 430.94 | 2.35 | 2.35 |
| 428.92 | 2.73 | 2.73 |
| 348.88 | 2.51 | 2.51 |
| 448.99 | 3.10 | 3.10 |
| 432.91 | 1.20 | 1.20 |
| 431.33 | 1.97 | 1.97 |