Inhibition of RIPK2 in MDP-stimulated human whole blood assessed as TNF-alpha level preincubated for 30 mins followed by MDP stimulation and measured ...

Basic Information

ID: ALA4316521

Type: Binding

Description: Inhibition of RIPK2 in MDP-stimulated human whole blood assessed as TNF-alpha level preincubated for 30 mins followed by MDP stimulation and measured after 6 hrs by immunoassay

Format: BAO_0000221

Organism: Homo sapiens

Tissue: Blood

Target: Serine/threonine-protein kinase RIPK2(ALA5014)

Document: ALA4312039

Inhibition of RIPK2 in MDP-stimulated human whole blood assessed as TNF-alpha level preincubated for 30 mins followed by MDP stimulation and measured after 6 hrs by immunoassay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4316521

IC50

Total(11)

Parent Molecular Weight	ALogP	Polar Surface Area
315.40	2.60	2.60
355.42	1.82	1.82
301.38	2.32	2.32
327.41	2.85	2.85
355.42	1.82	1.82
313.39	2.46	2.46
339.42	2.85	2.85
299.36	2.07	2.07
287.35	1.86	1.86
355.42	1.82	1.82
355.42	1.82	1.82

Parent Molecular Weight

ALogP

Polar Surface Area

315.40

2.60

355.42

1.82

301.38

2.32

327.41

2.85

355.42

1.82

313.39

2.46

339.42

2.85

299.36

2.07

287.35

1.86

355.42

1.82

355.42

1.82

Inhibition of RIPK2 in MDP-stimulated human whole blood assessed as TNF-alpha level preincubated for 30 mins followed by MDP stimulation and measured ...

Basic Information

Activity Charts

Compound Summary