Assay Report Card

Basic Information

ID: ALA4316545

Type: Binding

Description: Inhibition of His-tagged JMJD6 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as increase in H4 arginine 3 symmetrical dimethylation (H4R3me2s) content at 10 uM using core histone as substrate preincubated with enzyme for 10 mins followed by incubation with substrate for 1 hr by immunoblotting analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
273.313.233.23
281.291.871.87
272.352.382.38
277.283.043.04
338.372.722.72