Assay Report Card

Basic Information

ID: ALA4316686

Type: ADME

Description: Inhibition of UGT1A in rat hepatocytes assessed as decrease in bilirubin monoglucuronide level at 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis relative to control

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
482.825.695.69