Basic Information
ID: ALA4316845
Type: Functional
Description: Neuroprotective activity against amyloid beta (1 to 42)-induced neurodegeneration in human SH-SY5Y cells assessed as cell viability at 10 uM preincubated for 4 hrs followed by amyloid beta (1 to 42) addition and measured after 48 hrs by MTS assay (Rvb = 60.4%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: SH-SY5Y(ALA614910)
Document: ALA4316585
Neuroprotective activity against amyloid beta (1 to 42)-induced neurodegeneration in human SH-SY5Y cells assessed as cell viability at 10 uM preincubated for 4 hrs followed by amyloid beta (1 to 42) addition and measured after 48 hrs by MTS assay (Rvb = 60.4%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4316845
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.37 | 3.37 |
| 458.38 | 2.23 | 2.23 |
| 254.28 | 3.30 | 3.30 |
| 358.39 | 3.56 | 3.56 |
| 290.70 | 3.35 | 3.35 |
| 374.39 | 3.26 | 3.26 |
| 378.81 | 3.91 | 3.91 |
| 270.28 | 3.01 | 3.01 |
| 286.28 | 2.71 | 2.71 |
| 270.28 | 3.00 | 3.00 |