Basic Information
ID: ALA4316888
Type: Binding
Description: Inhibition of topoisomerase 1 (unknown origin) at 50 uM using pBR322 DNA as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by ethidium bromide staining-based agarose gel electrophoresis analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase I(ALA1781)
Document: ALA4316587
Inhibition of topoisomerase 1 (unknown origin) at 50 uM using pBR322 DNA as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by ethidium bromide staining-based agarose gel electrophoresis analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4316888
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.50 | 4.89 | 4.89 |
| 381.87 | 4.46 | 4.46 |
| 361.45 | 4.11 | 4.11 |
| 425.54 | 5.74 | 5.74 |
| 381.87 | 4.46 | 4.46 |
| 349.46 | 3.88 | 3.88 |
| 409.92 | 5.24 | 5.24 |
| 361.45 | 4.11 | 4.11 |
| 347.42 | 3.80 | 3.80 |
| 397.48 | 4.95 | 4.95 |
| 409.92 | 5.24 | 5.24 |
| 333.40 | 3.41 | 3.41 |
| 363.49 | 4.27 | 4.27 |
| 389.50 | 4.89 | 4.89 |