Basic Information
ID: ALA4321006
Type: ADME
Description: Permeability coefficient, ratio of total drug level in brain to plasma in Sprague-Dawley rat at 0.5 mg/kg, iv dosed via cassette dosing measured after 0.5 hrs
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Brain/Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4321006
Kp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.41 | 3.09 | 3.09 |
| 363.42 | 3.12 | 3.12 |
| 396.40 | 1.42 | 1.42 |
| 414.85 | 2.45 | 2.45 |
| 414.85 | 2.45 | 2.45 |
| 414.85 | 2.06 | 2.06 |
| 370.84 | 3.81 | 3.81 |
| 400.82 | 2.06 | 2.06 |
| 398.85 | 2.12 | 2.12 |
| 405.42 | 4.79 | 4.79 |
| 366.38 | 1.41 | 1.41 |
| 434.37 | 2.43 | 2.43 |
| 398.85 | 2.64 | 2.64 |
| 397.86 | 3.78 | 3.78 |
| 384.37 | 1.55 | 1.55 |
| 402.36 | 1.69 | 1.69 |
| 402.36 | 1.69 | 1.69 |
| 418.81 | 2.20 | 2.20 |
| 336.39 | 3.16 | 3.16 |
| 416.38 | 2.08 | 2.08 |
| 381.41 | 3.26 | 3.26 |
| 414.85 | 2.45 | 2.45 |
| 432.84 | 2.59 | 2.59 |
| 354.38 | 3.30 | 3.30 |
| 416.38 | 2.08 | 2.08 |
| 418.81 | 2.20 | 2.20 |
| 414.39 | 1.56 | 1.56 |
| 452.36 | 2.57 | 2.57 |
| 414.85 | 2.45 | 2.45 |
| 412.88 | 2.51 | 2.51 |
| 384.82 | 2.65 | 2.65 |
| 432.84 | 2.59 | 2.59 |