Basic Information
ID: ALA4321144
Type: Binding
Description: Inhibition of topoisomerase 2 in human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: DNA topoisomerase II(ALA2094255)
Document: ALA4316614
Inhibition of topoisomerase 2 in human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4321144
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 288.30 | 2.12 | 2.12 |
| 240.21 | 1.87 | 1.87 |
| 543.53 | 0.00 | 0.00 |
| 431.26 | 3.78 | 3.78 |
| 430.33 | 3.85 | 3.85 |
| 476.38 | 4.80 | 4.80 |
| 455.26 | 3.73 | 3.73 |
| 538.35 | 5.76 | 5.76 |
| 390.39 | 3.35 | 3.35 |
| 431.26 | 3.78 | 3.78 |
| 516.45 | 5.46 | 5.46 |
| 366.39 | 3.32 | 3.32 |
| 414.33 | 3.97 | 3.97 |
| 386.81 | 3.67 | 3.67 |
| 371.35 | 2.83 | 2.83 |
| 352.37 | 3.02 | 3.02 |
| 352.37 | 3.02 | 3.02 |
| 406.39 | 2.97 | 2.97 |
| 415.23 | 4.26 | 4.26 |
| 392.43 | 3.68 | 3.68 |
| 554.35 | 5.64 | 5.64 |