Basic Information
ID: ALA4321415
Type: Binding
Description: Inhibition of recombinant rat FAAH deltaTM mutant expressed in Escherichia coli using 14C-labeled oleamide as substrate preincubated for 3 hrs followed by substrate addition and measured by TLC based Dixon-plot analysis
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4321415
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.22 | 1.34 | 1.34 |
| 193.25 | 1.65 | 1.65 |
| 204.23 | 1.21 | 1.21 |
| 280.33 | 1.40 | 1.40 |
| 294.36 | 1.71 | 1.71 |
| 305.34 | 1.28 | 1.28 |
| 294.36 | 1.79 | 1.79 |
| 308.38 | 2.10 | 2.10 |
| 319.37 | 1.67 | 1.67 |
| 282.34 | 1.65 | 1.65 |
| 296.37 | 1.96 | 1.96 |
| 307.35 | 1.52 | 1.52 |
| 270.34 | 1.67 | 1.67 |
| 284.36 | 1.98 | 1.98 |
| 295.35 | 1.54 | 1.54 |
| 320.40 | 2.82 | 2.82 |
| 334.42 | 3.13 | 3.13 |
| 345.41 | 2.69 | 2.69 |
| 399.29 | 3.58 | 3.58 |
| 446.29 | 3.43 | 3.43 |
| 346.43 | 3.34 | 3.34 |
| 360.46 | 3.64 | 3.64 |
| 378.43 | 2.61 | 2.61 |
| 376.46 | 3.25 | 3.25 |
| 390.49 | 3.56 | 3.56 |
| 401.47 | 3.12 | 3.12 |
| 362.43 | 3.46 | 3.46 |
| 376.46 | 3.77 | 3.77 |
| 387.44 | 3.33 | 3.33 |
| 371.44 | 3.21 | 3.21 |
| 243.31 | 2.46 | 2.46 |
| 257.34 | 2.77 | 2.77 |
| 268.32 | 2.34 | 2.34 |
| 244.29 | 2.89 | 2.89 |
| 258.32 | 3.20 | 3.20 |
| 269.30 | 2.76 | 2.76 |
| 242.32 | 3.33 | 3.33 |
| 256.35 | 3.63 | 3.63 |
| 267.33 | 3.20 | 3.20 |
| 229.28 | 2.07 | 2.07 |
| 243.31 | 2.38 | 2.38 |
| 254.29 | 1.95 | 1.95 |
| 230.27 | 2.50 | 2.50 |
| 244.29 | 2.81 | 2.81 |
| 255.28 | 2.37 | 2.37 |
| 228.30 | 2.94 | 2.94 |
| 242.32 | 3.24 | 3.24 |
| 253.31 | 2.81 | 2.81 |
| 257.34 | 2.85 | 2.85 |
| 271.36 | 3.16 | 3.16 |
| 282.35 | 2.73 | 2.73 |
| 258.32 | 3.28 | 3.28 |
| 272.35 | 3.59 | 3.59 |
| 283.33 | 3.15 | 3.15 |
| 251.29 | 2.79 | 2.79 |
| 265.32 | 3.10 | 3.10 |
| 276.30 | 2.67 | 2.67 |
| 252.27 | 3.22 | 3.22 |
| 266.30 | 3.53 | 3.53 |
| 277.28 | 3.09 | 3.09 |
| 236.27 | 2.92 | 2.92 |
| 250.30 | 3.23 | 3.23 |
| 261.28 | 2.79 | 2.79 |
| 277.33 | 3.31 | 3.31 |
| 291.35 | 3.62 | 3.62 |
| 302.34 | 3.18 | 3.18 |
| 278.31 | 3.74 | 3.74 |
| 292.34 | 4.04 | 4.04 |
| 303.32 | 3.61 | 3.61 |
| 262.31 | 3.43 | 3.43 |
| 276.34 | 3.74 | 3.74 |
| 287.32 | 3.30 | 3.30 |
| 293.33 | 3.43 | 3.43 |
| 307.35 | 3.74 | 3.74 |
| 318.34 | 3.30 | 3.30 |
| 294.31 | 3.86 | 3.86 |
| 308.34 | 4.17 | 4.17 |
| 319.32 | 3.73 | 3.73 |
| 307.35 | 3.22 | 3.22 |
| 321.38 | 3.53 | 3.53 |
| 332.36 | 3.09 | 3.09 |
| 308.34 | 3.65 | 3.65 |
| 322.36 | 3.96 | 3.96 |
| 333.35 | 3.52 | 3.52 |
| 237.26 | 3.12 | 3.12 |
| 251.29 | 3.42 | 3.42 |
| 262.27 | 2.99 | 2.99 |
| 238.25 | 3.08 | 3.08 |
| 252.27 | 3.39 | 3.39 |
| 263.26 | 2.96 | 2.96 |
| 215.26 | 1.95 | 1.95 |
| 229.28 | 2.26 | 2.26 |
| 240.27 | 1.82 | 1.82 |
| 216.24 | 2.38 | 2.38 |
| 230.27 | 2.68 | 2.68 |
| 241.25 | 2.25 | 2.25 |
| 376.46 | 3.85 | 3.85 |
| 415.50 | 3.51 | 3.51 |
| 364.45 | 3.71 | 3.71 |
| 583.69 | 6.29 | 6.29 |
| 364.45 | 3.71 | 3.71 |
| 558.68 | 6.42 | 6.42 |
| 404.51 | 3.95 | 3.95 |
| 378.48 | 4.02 | 4.02 |
| 281.36 | 3.59 | 3.59 |
| 574.73 | 6.97 | 6.97 |
| 390.49 | 4.16 | 4.16 |
| 572.71 | 6.72 | 6.72 |
| 392.50 | 3.80 | 3.80 |
| 387.44 | 3.33 | 3.33 |
| 383.45 | 4.81 | 4.81 |
| 415.50 | 3.51 | 3.51 |
| 378.48 | 3.49 | 3.49 |
| 397.48 | 5.12 | 5.12 |
| 376.46 | 3.25 | 3.25 |
| 401.47 | 3.72 | 3.72 |
| 389.46 | 3.58 | 3.58 |
| 378.48 | 4.02 | 4.02 |
| 389.46 | 3.58 | 3.58 |
| 585.71 | 6.53 | 6.53 |
| 403.49 | 3.37 | 3.37 |
| 390.49 | 3.64 | 3.64 |
| 404.51 | 3.95 | 3.95 |
| 408.46 | 4.68 | 4.68 |
| 403.49 | 3.37 | 3.37 |
| 390.49 | 3.56 | 3.56 |
| 378.48 | 3.49 | 3.49 |
| 390.49 | 3.64 | 3.64 |
| 471.56 | 5.44 | 5.44 |
| 376.46 | 3.85 | 3.85 |
| 401.47 | 3.12 | 3.12 |
| 256.35 | 3.72 | 3.72 |
| 362.43 | 3.46 | 3.46 |
| 376.46 | 3.77 | 3.77 |
| 560.70 | 6.66 | 6.66 |
| 401.47 | 3.72 | 3.72 |
| 390.49 | 4.16 | 4.16 |
| 270.38 | 4.02 | 4.02 |
| 392.50 | 3.80 | 3.80 |
| 460.58 | 5.87 | 5.87 |
| 446.55 | 5.56 | 5.56 |