Basic Information
ID: ALA4322320
Type: Binding
Description: Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) cells preincubated for 1 hr followed by biotinylated Bim peptide addition measured after 2 hrs by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4322320
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 946.93 | 7.03 | 7.03 |
| 777.66 | 4.79 | 4.79 |
| 853.75 | 4.66 | 4.66 |
| 909.86 | 6.22 | 6.22 |
| 417.29 | 5.75 | 5.75 |
| 1023.02 | ||
| 587.54 | 7.08 | 7.08 |
| 833.77 | 6.35 | 6.35 |
| 493.38 | 5.34 | 5.34 |
| 937.91 | 7.00 | 7.00 |
| 941.86 | 4.69 | 4.69 |
| 881.81 | 5.44 | 5.44 |
| 805.71 | 5.57 | 5.57 |
| 865.76 | 4.83 | 4.83 |
| 569.48 | 5.20 | 5.20 |