Basic Information
ID: ALA4322323
Type: Binding
Description: Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 1 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: MCL1/Protein cereblon(ALA4523712)
Document: ALA4321796
Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 1 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4322323
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 479.36 | 5.25 | 5.25 |
| 946.93 | 7.03 | 7.03 |
| 777.66 | 4.79 | 4.79 |
| 853.75 | 4.66 | 4.66 |
| 909.86 | 6.22 | 6.22 |
| 1023.02 | ||
| 833.77 | 6.35 | 6.35 |
| 937.91 | 7.00 | 7.00 |
| 941.86 | 4.69 | 4.69 |
| 881.81 | 5.44 | 5.44 |
| 805.71 | 5.57 | 5.57 |
| 865.76 | 4.83 | 4.83 |