Basic Information
ID: ALA4322410
Type: Binding
Description: Modulation of mouse GATA4/mouse NKX2-5 protein-protein interaction expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as transcriptional synergy at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4322410
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.88 | 5.40 | 5.40 |
| 394.43 | 4.66 | 4.66 |
| 418.32 | 6.06 | 6.06 |
| 349.43 | 4.75 | 4.75 |
| 260.38 | 3.66 | 3.66 |
| 332.36 | 4.03 | 4.03 |
| 394.43 | 4.66 | 4.66 |
| 394.43 | 4.66 | 4.66 |
| 335.41 | 4.44 | 4.44 |
| 368.50 | 5.22 | 5.22 |
| 385.49 | 4.30 | 4.30 |
| 463.32 | 5.96 | 5.96 |
| 365.43 | 3.72 | 3.72 |
| 350.42 | 4.14 | 4.14 |
| 389.41 | 4.36 | 4.36 |
| 349.44 | 3.58 | 3.58 |
| 334.42 | 5.33 | 5.33 |
| 369.49 | 5.12 | 5.12 |
| 379.53 | 5.94 | 5.94 |
| 349.43 | 4.75 | 4.75 |
| 434.36 | 5.57 | 5.57 |
| 393.49 | 3.69 | 3.69 |
| 323.39 | 4.67 | 4.67 |
| 389.41 | 5.18 | 5.18 |
| 348.45 | 5.35 | 5.35 |
| 353.42 | 4.65 | 4.65 |
| 367.52 | 5.25 | 5.25 |
| 322.41 | 3.74 | 3.74 |
| 349.44 | 3.58 | 3.58 |
| 354.41 | 4.04 | 4.04 |
| 319.39 | 3.75 | 3.75 |
| 321.38 | 4.82 | 4.82 |
| 428.33 | 5.51 | 5.51 |
| 333.44 | 5.25 | 5.25 |
| 302.33 | 3.88 | 3.88 |
| 301.39 | 3.64 | 3.64 |
| 422.44 | 5.68 | 5.68 |
| 395.48 | 5.11 | 5.11 |
| 363.46 | 5.14 | 5.14 |
| 369.49 | 5.12 | 5.12 |
| 339.40 | 4.34 | 4.34 |
| 439.56 | 6.34 | 6.34 |
| 377.49 | 5.05 | 5.05 |
| 398.51 | 4.83 | 4.83 |
| 349.44 | 3.67 | 3.67 |
| 408.46 | 5.05 | 5.05 |
| 432.45 | 5.33 | 5.33 |
| 354.41 | 4.04 | 4.04 |
| 337.34 | 4.20 | 4.20 |
| 326.36 | 1.48 | 1.48 |
| 403.44 | 4.75 | 4.75 |
| 431.46 | 5.59 | 5.59 |
| 365.43 | 5.04 | 5.04 |
| 354.41 | 4.04 | 4.04 |
| 374.52 | ||
| 337.42 | 5.33 | 5.33 |
| 354.41 | 5.57 | 5.57 |
| 367.42 | 4.89 | 4.89 |
| 351.40 | 4.80 | 4.80 |
| 350.42 | 4.14 | 4.14 |
| 363.46 | 4.77 | 4.77 |
| 505.40 | 5.27 | 5.27 |
| 481.31 | 6.83 | 6.83 |
| 378.48 | 4.72 | 4.72 |
| 274.39 | 3.85 | 3.85 |
| 411.55 | 6.28 | 6.28 |
| 325.37 | 4.03 | 4.03 |
| 364.45 | 4.71 | 4.71 |
| 443.52 | 6.55 | 6.55 |
| 335.41 | 4.44 | 4.44 |
| 355.46 | 4.81 | 4.81 |
| 341.44 | 4.66 | 4.66 |
| 365.39 | 3.97 | 3.97 |
| 352.46 | 4.30 | 4.30 |
| 352.44 | 4.09 | 4.09 |
| 364.51 | 5.82 | 5.82 |
| 479.58 | 6.61 | 6.61 |
| 366.38 | 3.88 | 3.88 |
| 380.44 | 3.68 | 3.68 |
| 365.50 | 5.28 | 5.28 |
| 379.53 | 5.31 | 5.31 |
| 349.48 | 5.13 | 5.13 |
| 322.32 | 3.60 | 3.60 |
| 333.44 | 5.25 | 5.25 |
| 396.49 | 5.40 | 5.40 |
| 376.41 | 4.69 | 4.69 |
| 348.45 | 4.19 | 4.19 |
| 383.88 | 5.40 | 5.40 |
| 335.45 | 5.11 | 5.11 |
| 321.38 | 3.97 | 3.97 |
| 367.57 | 4.69 | 4.69 |
| 335.45 | 5.11 | 5.11 |
| 361.36 | 3.58 | 3.58 |
| 407.47 | 3.61 | 3.61 |
| 375.52 | 5.69 | 5.69 |
| 353.43 | 3.48 | 3.48 |
| 336.35 | 3.69 | 3.69 |
| 310.31 | 4.14 | 4.14 |
| 393.44 | 3.62 | 3.62 |