Basic Information
ID: ALA4322411
Type: Binding
Description: Modulation of mouse NKX2-5 expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as protein-induced transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Mus musculus
Target: Homeobox protein Nkx-2.5(ALA4105872)
Document: ALA4321800
Modulation of mouse NKX2-5 expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as protein-induced transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4322411
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.88 | 5.40 | 5.40 |
| 394.43 | 4.66 | 4.66 |
| 418.32 | 6.06 | 6.06 |
| 349.43 | 4.75 | 4.75 |
| 260.38 | 3.66 | 3.66 |
| 332.36 | 4.03 | 4.03 |
| 394.43 | 4.66 | 4.66 |
| 394.43 | 4.66 | 4.66 |
| 335.41 | 4.44 | 4.44 |
| 368.50 | 5.22 | 5.22 |
| 385.49 | 4.30 | 4.30 |
| 463.32 | 5.96 | 5.96 |
| 365.43 | 3.72 | 3.72 |
| 350.42 | 4.14 | 4.14 |
| 389.41 | 4.36 | 4.36 |
| 349.44 | 3.58 | 3.58 |
| 334.42 | 5.33 | 5.33 |
| 369.49 | 5.12 | 5.12 |
| 379.53 | 5.94 | 5.94 |
| 349.43 | 4.75 | 4.75 |
| 434.36 | 5.57 | 5.57 |
| 393.49 | 3.69 | 3.69 |
| 323.39 | 4.67 | 4.67 |
| 389.41 | 5.18 | 5.18 |
| 348.45 | 5.35 | 5.35 |
| 353.42 | 4.65 | 4.65 |
| 367.52 | 5.25 | 5.25 |
| 322.41 | 3.74 | 3.74 |
| 349.44 | 3.58 | 3.58 |
| 354.41 | 4.04 | 4.04 |
| 321.38 | 4.82 | 4.82 |
| 428.33 | 5.51 | 5.51 |
| 333.44 | 5.25 | 5.25 |
| 302.33 | 3.88 | 3.88 |
| 422.44 | 5.68 | 5.68 |
| 395.48 | 5.11 | 5.11 |
| 369.49 | 5.12 | 5.12 |
| 339.40 | 4.34 | 4.34 |
| 439.56 | 6.34 | 6.34 |
| 377.49 | 5.05 | 5.05 |
| 398.51 | 4.83 | 4.83 |
| 349.44 | 3.67 | 3.67 |
| 408.46 | 5.05 | 5.05 |
| 432.45 | 5.33 | 5.33 |
| 354.41 | 4.04 | 4.04 |
| 337.34 | 4.20 | 4.20 |
| 326.36 | 1.48 | 1.48 |
| 431.46 | 5.59 | 5.59 |
| 365.43 | 5.04 | 5.04 |
| 354.41 | 4.04 | 4.04 |
| 374.52 | ||
| 337.42 | 5.33 | 5.33 |
| 354.41 | 5.57 | 5.57 |
| 367.42 | 4.89 | 4.89 |
| 309.32 | 3.93 | 3.93 |
| 351.40 | 4.80 | 4.80 |
| 350.42 | 4.14 | 4.14 |
| 363.46 | 4.77 | 4.77 |
| 505.40 | 5.27 | 5.27 |
| 481.31 | 6.83 | 6.83 |
| 378.48 | 4.72 | 4.72 |
| 274.39 | 3.85 | 3.85 |
| 411.55 | 6.28 | 6.28 |
| 299.37 | 3.65 | 3.65 |
| 325.37 | 4.03 | 4.03 |
| 364.45 | 4.71 | 4.71 |
| 443.52 | 6.55 | 6.55 |
| 335.41 | 4.44 | 4.44 |
| 355.46 | 4.81 | 4.81 |
| 341.44 | 4.66 | 4.66 |
| 365.39 | 3.97 | 3.97 |
| 352.46 | 4.30 | 4.30 |
| 364.51 | 5.82 | 5.82 |
| 479.58 | 6.61 | 6.61 |
| 366.38 | 3.88 | 3.88 |
| 380.44 | 3.68 | 3.68 |
| 365.50 | 5.28 | 5.28 |
| 379.53 | 5.31 | 5.31 |
| 349.48 | 5.13 | 5.13 |
| 322.32 | 3.60 | 3.60 |
| 333.44 | 5.25 | 5.25 |
| 332.45 | 3.85 | 3.85 |
| 396.49 | 5.40 | 5.40 |
| 376.41 | 4.69 | 4.69 |
| 348.45 | 4.19 | 4.19 |
| 383.88 | 5.40 | 5.40 |
| 335.45 | 5.11 | 5.11 |
| 321.38 | 3.97 | 3.97 |
| 367.57 | 4.69 | 4.69 |
| 335.45 | 5.11 | 5.11 |
| 361.36 | 3.58 | 3.58 |
| 407.47 | 3.61 | 3.61 |
| 375.52 | 5.69 | 5.69 |
| 353.43 | 3.48 | 3.48 |
| 336.35 | 3.69 | 3.69 |
| 310.31 | 4.14 | 4.14 |
| 393.44 | 3.62 | 3.62 |