Basic Information
ID: ALA4322495
Type: Binding
Description: Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysis
Organism: Homo sapiens
Cell type: A2058
Activity Charts
Bioactivity
Activity Types for Assay ALA4322495
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.39 | 1.21 | 1.21 |
| 445.47 | 2.19 | 2.19 |
| 369.43 | 0.50 | 0.50 |
| 420.44 | 2.89 | 2.89 |
| 420.44 | 2.89 | 2.89 |
| 368.44 | 1.11 | 1.11 |
| 380.45 | 1.25 | 1.25 |
| 382.47 | 1.42 | 1.42 |
| 420.44 | 2.89 | 2.89 |
| 380.45 | 1.25 | 1.25 |
| 354.41 | 0.72 | 0.72 |
| 443.51 | 0.79 | 0.79 |
| 354.41 | 0.72 | 0.72 |
| 354.41 | 0.72 | 0.72 |
| 422.41 | 1.74 | 1.74 |
| 368.44 | 1.11 | 1.11 |
| 398.47 | 1.12 | 1.12 |
| 422.41 | 1.74 | 1.74 |
| 382.47 | 1.42 | 1.42 |
| 369.43 | 0.50 | 0.50 |
| 368.44 | 1.11 | 1.11 |
| 420.44 | 2.89 | 2.89 |
| 442.52 | 1.40 | 1.40 |
| 382.47 | 1.50 | 1.50 |
| 354.41 | 0.72 | 0.72 |
| 380.45 | 1.25 | 1.25 |
| 380.45 | 1.25 | 1.25 |
| 382.47 | 1.50 | 1.50 |
| 368.44 | 1.11 | 1.11 |