Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by W...

Basic Information

ID: ALA4322496

Type: Binding

Description: Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: A2058

Target: mTORC1(ALA4296661)

Document: ALA4321805

Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by Western blot analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4322496

IC50

Total(29)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
411.39	1.21	1.21
445.47	2.19	2.19
369.43	0.50	0.50
420.44	2.89	2.89
420.44	2.89	2.89
368.44	1.11	1.11
380.45	1.25	1.25
382.47	1.42	1.42
420.44	2.89	2.89
380.45	1.25	1.25
354.41	0.72	0.72
443.51	0.79	0.79
354.41	0.72	0.72
354.41	0.72	0.72
422.41	1.74	1.74
368.44	1.11	1.11
398.47	1.12	1.12
422.41	1.74	1.74
382.47	1.42	1.42
369.43	0.50	0.50
368.44	1.11	1.11
420.44	2.89	2.89
442.52	1.40	1.40
382.47	1.50	1.50
354.41	0.72	0.72
380.45	1.25	1.25
380.45	1.25	1.25
382.47	1.50	1.50
368.44	1.11	1.11