Assay Report Card

Basic Information

ID: ALA4323246

Type: Binding

Description: Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11 cells expressing wild type p53 assessed as decrease in GSPT1 protein level by measuring log ratio of protein level before and after treatment at 0.1 uM measured after 3 hrs relative to control

Organism: Homo sapiens

Cell type: RS4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
774.726.076.07