Basic Information
ID: ALA4323250
Type: Binding
Description: Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as decrease in GSPT1 protein level at 10 nM by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4323250
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 893.84 | 7.32 | 7.32 |
| 774.72 | 6.07 | 6.07 |