Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as effect on GSPT1 mRNA level...

Basic Information

ID: ALA4323252

Type: Binding

Description: Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as effect on GSPT1 mRNA level after 3 hrs by qRT-PCR analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Cereblon/GSPT1/Cullin-4A/DDB1(ALA4524003)

Document:  ALA4321819

Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as effect on GSPT1 mRNA level after 3 hrs by qRT-PCR analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
774.726.076.07