Assay Report Card

Basic Information

ID: ALA4323253

Type: Binding

Description: Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11 cells expressing wild type p53 assessed as decrease in GSPT1 protein level at 1 to 3 uM after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: RS4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
704.595.185.18
746.675.295.29