Basic Information
ID: ALA4323254
Type: Binding
Description: Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as decrease in GSPT1 protein level at 1 to 3 uM after 24 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4323254
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 704.59 | 5.18 | 5.18 |
| 746.67 | 5.29 | 5.29 |