Basic Information
ID: ALA4323256
Type: Binding
Description: Protac activity at GSPT1/CUL4/DDB1/CRBN in human RS4:11/IRMI-2 cells harboring p53 hotspot mutation Y236H/R249G assessed as decrease in GSPT1 protein level after 2 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4323256
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.38 | 4.53 | 4.53 |
| 834.77 | 5.32 | 5.32 |
| 790.72 | 5.31 | 5.31 |
| 760.69 | 5.68 | 5.68 |
| 774.72 | 6.07 | 6.07 |
| 878.83 | 5.34 | 5.34 |