ID: ALA4323791
Type: Binding
Description: Negative allosteric modulation of human luteinizing hormone receptor assessed as Emax for glycoprotein human luteinizing hormone-induced agonist activity at 0.84 nM to 17 uM preincubated for 20 mins followed by 100 times EC80 of agonist addition and measured after 60 mins by cell based TR-FRET assay relative to control
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4323791
Emax
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
473.94 | 6.85 | 6.85 |