Basic Information
ID: ALA4323797
Type: Functional
Description: Antagonist activity at human thyroid stimulating hormone receptor expressed in rat HTC133 cells assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed by agonist solution addition and measured after 60 mins by cell based TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4323797
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.36 | 6.24 | 6.24 |
| 459.46 | 5.12 | 5.12 |
| 433.36 | 6.24 | 6.24 |
| 473.94 | 6.85 | 6.85 |
| 433.36 | 6.24 | 6.24 |