Assay Report Card

Basic Information

ID: ALA4324021

Type: Functional

Description: Antitumor activity against human SET2 cells overexpressing JAK2 V617F mutant xenografted in NOD/SCID mouse assessed as tumor growth inhibition at 60 mg/kg, po qd for 18 days measured every 2 days for 18 days by caliper method relative to control

Organism: Homo sapiens

Cell type: SET-2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
467.594.014.01