Basic Information
ID: ALA4324034
Type: ADME
Description: Poison activity at topoisomerase 2alpha in human SW620 cells assessed as induction of DNA double stranded break by measuring gamma H2AX phosphorylation up to 40 uM after 6 hrs by Hoechst-33342 staining based immunofluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4321838
Poison activity at topoisomerase 2alpha in human SW620 cells assessed as induction of DNA double stranded break by measuring gamma H2AX phosphorylation up to 40 uM after 6 hrs by Hoechst-33342 staining based immunofluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324034
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 313.32 | 2.69 | 2.69 |
| 312.30 | 3.41 | 3.41 |