Basic Information
ID: ALA4324043
Type: Binding
Description: Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by luciferase based TOPFlash reporter gene assay
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4321838
Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by luciferase based TOPFlash reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324043
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.44 | 3.62 | 3.62 |
| 427.46 | 4.83 | 4.83 |
| 335.36 | 3.52 | 3.52 |
| 318.33 | 4.31 | 4.31 |
| 417.47 | 4.01 | 4.01 |
| 312.30 | 3.41 | 3.41 |
| 320.39 | 4.59 | 4.59 |
| 411.43 | 3.11 | 3.11 |
| 284.34 | 3.63 | 3.63 |
| 268.27 | 3.16 | 3.16 |