Basic Information
ID: ALA4324048
Type: Binding
Description: Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal transition by measuring increase in E-cadherin expression up to 40 uM after 72 hrs by Hoechst 33342 staining based mCherryRFP reporter gene assay
Format: BAO_0000019
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4321838
Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal transition by measuring increase in E-cadherin expression up to 40 uM after 72 hrs by Hoechst 33342 staining based mCherryRFP reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324048
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.44 | 3.62 | 3.62 |
| 312.30 | 3.41 | 3.41 |
| 411.43 | 3.11 | 3.11 |