Basic Information
ID: ALA4324119
Type: Binding
Description: Inhibition of human recombinant GST-tagged wild type EGFR expressed in baculovirus expression system assessed as decrease in phosphorylation of ULight-poly-GT using ULight-poly-GT as substrate incubated for 90 mins in presence of ATP by TR-FRET LANCE assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4321840
Inhibition of human recombinant GST-tagged wild type EGFR expressed in baculovirus expression system assessed as decrease in phosphorylation of ULight-poly-GT using ULight-poly-GT as substrate incubated for 90 mins in presence of ATP by TR-FRET LANCE assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324119
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.46 | 3.54 | 3.54 |
| 386.46 | 3.54 | 3.54 |
| 387.44 | 2.94 | 2.94 |
| 390.45 | 2.28 | 2.28 |
| 417.47 | 2.95 | 2.95 |
| 404.45 | 3.68 | 3.68 |