Basic Information
ID: ALA4324151
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 2 hrs followed by LPS-stimulation and further incubated for 5.5 hrs and subsequently ATP addition and measured after 30 mins by ELISA method
Format: BAO_0000219
Organism: Mus musculus
Target: NACHT, LRR and PYD domains-containing protein 3(ALA3779755)
Document: ALA4321841
Inhibition of NLRP3 inflammasome activation in mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 2 hrs followed by LPS-stimulation and further incubated for 5.5 hrs and subsequently ATP addition and measured after 30 mins by ELISA method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324151
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.84 | 1.99 | 1.99 |