Basic Information
ID: ALA4324155
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 10 mins followed by addition of nigericin
Format: BAO_0000019
Organism: Homo sapiens
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA4321841
Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 10 mins followed by addition of nigericin: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324155
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.51 |