ID: ALA4324160
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by addition of ATP and measured after 30 mins by ELISA method
Format: BAO_0000019
Organism: Mus musculus
Target: NACHT, LRR and PYD domains-containing protein 3(ALA3779755)
Document: ALA4321841
Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by addition of ATP and measured after 30 mins by ELISA method: 1
Bioactivity
Activity Types for Assay ALA4324160
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
267.24 | 2.50 | 2.50 |
253.26 | 2.50 | 2.50 |