Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed b...

Basic Information

ID: ALA4324160

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by addition of ATP and measured after 30 mins by ELISA method

Format: BAO_0000019

Organism: Mus musculus

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA3779755)

Document:  ALA4321841

Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by addition of ATP and measured after 30 mins by ELISA method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
267.242.502.50
253.262.502.50