Basic Information
ID: ALA4324176
Type: Binding
Description: Selectivity index, ratio of IC50 for recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli to IC50 for recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4321842
Selectivity index, ratio of IC50 for recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli to IC50 for recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324176
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.43 | 2.91 | 2.91 |
| 410.93 | 5.52 | 5.52 |
| 502.62 | 3.33 | 3.33 |
| 473.58 | 3.56 | 3.56 |
| 349.39 | 1.74 | 1.74 |
| 459.59 | 4.47 | 4.47 |
| 566.17 | 7.18 | 7.18 |
| 501.63 | 4.31 | 4.31 |
| 495.61 | 2.40 | 2.40 |
| 420.47 | 2.01 | 2.01 |
| 515.66 | 4.62 | 4.62 |
| 487.60 | 3.66 | 3.66 |
| 547.66 | 5.43 | 5.43 |
| 360.42 | 2.69 | 2.69 |
| 488.59 | 3.57 | 3.57 |
| 382.45 | 1.73 | 1.73 |
| 583.16 | 8.67 | 8.67 |
| 427.91 | 3.84 | 3.84 |
| 374.44 | 3.00 | 3.00 |
| 473.46 | 2.81 | 2.81 |
| 398.92 | 5.33 | 5.33 |
| 384.89 | 4.99 | 4.99 |
| 419.53 | 3.55 | 3.55 |
| 427.49 | 0.83 | 0.83 |
| 405.46 | 2.00 | 2.00 |
| 480.59 | 3.32 | 3.32 |
| 469.57 | 1.86 | 1.86 |
| 453.95 | 4.38 | 4.38 |
| 448.53 | 2.01 | 2.01 |
| 476.58 | 2.97 | 2.97 |
| 434.50 | 1.59 | 1.59 |
| 538.11 | 6.57 | 6.57 |
| 569.63 | 5.33 | 5.33 |
| 428.41 | 3.71 | 3.71 |
| 555.60 | 5.40 | 5.40 |
| 530.67 | 3.93 | 3.93 |
| 392.42 | 0.60 | 0.60 |
| 363.42 | 2.09 | 2.09 |
| 335.37 | 1.48 | 1.48 |
| 487.60 | 4.38 | 4.38 |
| 418.46 | 1.13 | 1.13 |
| 419.49 | 2.10 | 2.10 |
| 406.45 | 0.99 | 0.99 |
| 501.63 | 4.69 | 4.69 |
| 462.55 | 2.40 | 2.40 |
| 447.54 | 3.03 | 3.03 |
| 448.53 | 2.16 | 2.16 |
| 405.46 | 1.80 | 1.80 |
| 541.57 | 4.38 | 4.38 |
| 498.05 | 5.65 | 5.65 |
| 494.62 | 3.20 | 3.20 |
| 515.54 | 3.84 | 3.84 |
| 375.43 | 2.28 | 2.28 |
| 484.02 | 5.26 | 5.26 |
| 454.56 | 2.79 | 2.79 |
| 441.94 | 4.23 | 4.23 |
| 455.02 | 6.80 | 6.80 |
| 462.55 | 3.04 | 3.04 |
| 547.60 | 5.15 | 5.15 |
| 367.43 | 2.66 | 2.66 |
| 461.57 | 3.13 | 3.13 |
| 412.48 | 1.76 | 1.76 |
| 487.60 | 4.58 | 4.58 |
| 370.86 | 4.73 | 4.73 |
| 484.02 | 5.40 | 5.40 |
| 494.62 | 3.41 | 3.41 |
| 562.62 | 4.22 | 4.22 |
| 479.61 | 4.33 | 4.33 |
| 508.65 | 3.51 | 3.51 |
| 389.46 | 2.84 | 2.84 |
| 495.09 | 7.72 | 7.72 |
| 502.62 | 3.50 | 3.50 |
| 434.50 | 1.94 | 1.94 |
| 479.61 | 4.13 | 4.13 |
| 501.63 | 4.51 | 4.51 |
| 360.42 | 2.90 | 2.90 |
| 473.58 | 3.36 | 3.36 |
| 469.99 | 4.84 | 4.84 |
| 493.63 | 4.44 | 4.44 |
| 447.54 | 2.82 | 2.82 |