Basic Information
ID: ALA4324209
Type: Binding
Description: Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-binding method
Format: BAO_0000357
Organism: Homo sapiens
Target: Mitogen-activated protein kinase kinase kinase 5(ALA5285)
Document: ALA4321844
Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-binding method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324209
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.32 | 2.97 | 2.97 |
| 445.50 | 4.68 | 4.68 |
| 349.39 | 3.01 | 3.01 |
| 349.39 | 3.16 | 3.16 |
| 509.56 | 6.19 | 6.19 |
| 325.35 | 3.31 | 3.31 |
| 472.55 | 3.19 | 3.19 |
| 349.39 | 3.01 | 3.01 |
| 510.55 | 5.59 | 5.59 |
| 353.36 | 2.90 | 2.90 |
| 321.34 | 2.37 | 2.37 |
| 413.46 | 2.17 | 2.17 |
| 415.46 | 3.17 | 3.17 |
| 349.39 | 3.33 | 3.33 |
| 309.33 | 2.14 | 2.14 |
| 349.39 | 3.33 | 3.33 |
| 367.38 | 3.15 | 3.15 |
| 432.48 | 2.60 | 2.60 |
| 420.47 | 2.60 | 2.60 |
| 335.37 | 2.77 | 2.77 |
| 367.38 | 3.47 | 3.47 |
| 349.39 | 3.15 | 3.15 |
| 415.46 | 3.26 | 3.26 |
| 353.36 | 2.90 | 2.90 |
| 414.26 | 3.53 | 3.53 |
| 504.57 | 3.58 | 3.58 |