Basic Information
ID: ALA4324329
Type: Functional
Description: Antitumor activity against human Calu6 cells expressing KRAS Q61K mutant xenografted in athymic Nude-Foxn1nu mouse assessed as tumor growth inhibition at 15 mg/kg, po qd adminstered for 21 days and measured twice per week by caliper method relative to control
Format: BAO_0000218
Organism: Homo sapiens
Cell type: Calu-6
Target: Calu-6(ALA614535)
Document: ALA4321846
Antitumor activity against human Calu6 cells expressing KRAS Q61K mutant xenografted in athymic Nude-Foxn1nu mouse assessed as tumor growth inhibition at 15 mg/kg, po qd adminstered for 21 days and measured twice per week by caliper method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324329
TGI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.51 | 3.07 | 3.07 |