Basic Information
ID: ALA4324331
Type: Functional
Description: Reduction in phosphorylated RSK level in athymic Nude-Foxn1nu mouse xenografted with human Calu6 cells expressing KRAS Q61K mutant at 25 mg/kg, po qd adminstered for 21 days and measured after 0.5 hrs post dose by Western blot analysis relative to control
Format: BAO_0000218
Organism: Mus musculus
Target: Mus musculus(ALA375)
Document: ALA4321846
Reduction in phosphorylated RSK level in athymic Nude-Foxn1nu mouse xenografted with human Calu6 cells expressing KRAS Q61K mutant at 25 mg/kg, po qd adminstered for 21 days and measured after 0.5 hrs post dose by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324331
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.51 | 3.07 | 3.07 |