Basic Information
ID: ALA4324368
Type: Binding
Description: Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells using nicotinamide as substrate preincubated for 10 mins in presence of AdoMet followed by substrate addition by fluorescence based SAHH-coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4324368
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 121.14 | 0.79 | 0.79 |
| 514.54 | -1.53 | -1.53 |
| 528.57 | -1.14 | -1.14 |
| 556.62 | -0.36 | -0.36 |
| 554.56 | -1.71 | -1.71 |
| 524.54 | -1.72 | -1.72 |
| 535.61 | 0.92 | 0.92 |
| 521.58 | 0.53 | 0.53 |
| 423.43 | -1.23 | -1.23 |
| 538.57 | -1.41 | -1.41 |
| 549.63 | 1.31 | 1.31 |
| 542.60 | -0.83 | -0.83 |
| 542.60 | -0.75 | -0.75 |
| 542.60 | -0.83 | -0.83 |
| 542.60 | -0.75 | -0.75 |
| 549.63 | 1.31 | 1.31 |
| 543.58 | -0.45 | -0.45 |
| 535.61 | 0.92 | 0.92 |