Basic Information
ID: ALA4324417
Type: Binding
Description: Potency index, ratio of Ki for MS2756 to Ki for test compound for inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells using nicotinamide as substrate preincubated for 10 mins in presence of AdoMet followed by substrate addition by fluorescence based SAHH enzyme coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4324417
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.57 | -1.14 | -1.14 |
| 524.54 | -1.72 | -1.72 |
| 542.60 | -0.75 | -0.75 |