Basic Information
ID: ALA4324469
Type: Binding
Description: Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulated IL-17 secretion after 48 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HuT78
Target: Nuclear receptor ROR-gamma(ALA1741186)
Document: ALA4321852
Inhibition of human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal antibody stimulated IL-17 secretion after 48 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324469
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 351.86 | 4.31 | 4.31 |
| 370.23 | 4.57 | 4.57 |
| 508.71 | 6.33 | 6.33 |
| 482.80 | 6.12 | 6.12 |
| 550.79 | 7.52 | 7.52 |
| 514.38 | 6.26 | 6.26 |
| 494.68 | 5.94 | 5.94 |
| 383.28 | 6.34 | 6.34 |
| 395.59 | 6.42 | 6.42 |
| 349.26 | 5.95 | 5.95 |
| 493.70 | 5.34 | 5.34 |